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Announcing Sacred Mounds, a novel of Magical Realism and Historical Fantasy from Jim Metzner, with a foreword by Hutke Fields, principal chief of the Natchez Nation.
Cyclonic hordes of insects, a telepathic despot, body-swapping sex - just a few of the surprises Salvador Samuels encounters when he is swept back to pre-colonial times, walking in the moccasins of a blind Indian - who, in turn, has been transported into Salvador's body in present-day America. Sacred Mounds Book Cover Four hundred years apart, they are bound by a mission to rescue our world, aided by the mysterious presence of the mounds. Thousands of these ancient earthworks once dotted the landscape of North America. We still don't know why they were created. Sacred Mounds suggests they are as important today as when they were made over a thousand years ago. Sacred Mounds weaves the stories of two men, each a stranger in a strange land. With the help of two remarkable women, they must find a way to save our planet and return home.
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Strokes - Drugs to Prevent: The Pulse of the Planet daily radio program offers free legal online mp3 downloads, exploring the world of sound in nature, culture and science, with audio adventures, world music, extraordinary sound portraits, science diaries, and nature ring-tones; an amazing sonic experience.



Airdate: Feb 15, 2016
Scientist: Michelle Theus

Strokes - Drugs to Prevent

Strokes - Drugs to Prevent
Scientists are trying to develop a drug that could help stroke patients maximize whatever bypass arteries they may have.

Transcript:
Preventing StrokesWhen there's a blockage in the arteries in our brain, it can cause a stroke. Some people possess a backup network of arteries, called collaterals, that can re-route blood flow after a stroke and help the brain to heal. I'm Jim Metzner and this is the Pulse of the Planet. Not everyone has these collateral arteries in their brain and scientists are trying to figure out why.Theus: Our working hypothesis is that during development that the growth of these bypass or collateral vessels is influenced by the immune cells of the embryo, which could be regulated by environmental factors of the mother. Dr. Michelle Theus is an assistant professor in the College of Veterinary Medicine at Virginia Tech. Theus: Perhaps in the future a dietary supplement or a change in diet of the mother, or a pharmaceutical drug could potentially influence the developing fetuses' collateral system.Dr Theus and her team are also trying to develop a drug that could help stroke patients maximize whatever bypass arteries they may have.Theus: We've identified one protein in the brain that we believe is an inhibitory signal to prevent those bypass vessels from enlarging or doing their job. We may potentially have a drug that blocks that protein, thereby allowing the bypass system to enlarge and reroute blood flow and establish a proper functioning brain.These drugs that we're looking at in the laboratory, they don't last very long in the bloodstream. One way that we're trying to not only get it to the brain, but were trying to enhance its longevity in the brain - is to tag it to a nanoparticle. So we can not only hopefully prevent the early stages of stroke, but these particles may stick around longer to help the brain recover in the long-term.I'm Jim Metzner and this is the Pulse of the Planet.